Primary Large Diffuse B Cell Lymphoma Presenting as Rapidly Enlarging Thyroid Mass with Compressive Symptoms: A Case Report

Background: Primary thyroid lymphoma are seen occasionally accounting for 5% among tumors. Commonest of these lymphomas is diffuse large B cell type. Case report: A 66 years old female presented to our Department with rapidly enlarging mass having difficulty in swallowing as well breathing. She underwent left hemithyroidectomy 30 ago a benign disease. Clinicallly it was 20 × cm hard inconsistency and clinically attached sternocleidomastoid muscles no skin lymph node involvement. Computed Tomography (CT) scan neck contrast showed ill-defined noted arising from the right lobe gland encasing common carotid loss fat planes between jugular vein, sternocleidomastoid, trachea, esophagus suggesting incisional biopsy which Diffuse Large Cell Lymphoma (DLBCL). Discussion: Most originate cells. Fine Needle Aspiration Cytology (FNAC) can diagnose 80-85% cases but definitive diagnosis be made by only. Surgery has limited role treatment main modality chemoradiotherapy. Conclusion: enlarged swelling should suspected specially on background lymphocytic thyroiditis multidisciplinary team approach used management.